Croatica Chemica Acta

Croatica Chemica Acta

A Theoretical Information Approach to Ring and Total Aromaticity' in Ground and Excited States

ors: A. Graovac and N. Trinajstic published in Croatica Chemica Acta 53 (4) 581 586 (1980) I Serial rm 581 586 Analytic m Sep. 3, 1979 539.19:547.53 ml~ January 1981 YU 0011-1643 m English m CCACAA rm Croat. Engl.

How Surface Heterogeneity Affects Protein Adsorption: Annealing of OTS Patterns and Albumin Adsorption Kinetics.

Fluorescence microscopy and intensity histogram analysis techniques were used to monitor spatially-resolved albumin adsorption kinetics to model heterogeneous surfaces on sub-μm scales. Several distinct protein subpopulations were resolved, each represented by a normal distribution of adsorption densities on the adsorbent surface. Histogram analyses provided dynamic information of mean adsorpti...

Croatica Chemica Acta

Some basic algebraic features of quasiparticle transformations are reviewed. Special nonlinear quasiparticle transformations are introduced leading to the second quantized counterparts of gerninal-type (correlated) wave functions. Algebraic representa-' tions of strong and weak orthogonality are discussed, and these issues are generalized to the case of non-orthogonal basis sets leading to the ...

Single Molecule Probing of Exocytotic Protein Interactions Using Force Spectroscopy.

Relatively recently, the Atomic Force Microscope (AFM) emerged as a powerful tool for single molecule nanomechanical investigations. Parameters that can be measured by force spectroscopy using AFM, such as the force and total mechanical extension required to break bonds between various proteins can yield valuable insights into the nature of the bond (zippering vs. highly localized binding site)...

Lack of discrimination against non-proteinogenic amino acid norvaline by elongation factor Tu from Escherichia coli.

The GTP-bound form of elongation factor Tu (EF-Tu) brings aminoacylated tRNAs (aa-tRNA) to the A-site of the ribosome. EF-Tu binds all cognate elongator aa-tRNAs with highly similar affinities, and its weaker or tighter binding of misacylated tRNAs may discourage their participation in translation. Norvaline (Nva) is a non-proteinogenic amino acid that is activated and transferred to tRNALeu by...